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  1. Disclaimer: Healthline has made every effort ampicillin uses to make certain that all information is factually correct, comprehensive, and up-to-date. Uses : -Parenteral: For the treatment of bacterial meningitis due to Escherichia coli, group ampicillin uses B streptococci, and other gram-negative bacteria (Listeria monocytogenes, Neisseria meningitidis) -Oral: For the treatment of meningitis due to N meningitidis.